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Violation of the concentration of norepinephrine, dopamine, serotonin underlies depression. This conclusion was made as a result of experiments on the action of antidepressants. But two more mediators: gamma- aminobutyric acid and glutamate are involved in the mechanism of the development of depression. Lamotrigine , ketamine, amantadine and anticonvulsants affect the severity of depression by affecting the glutamate receptors . Stress also plays an important role in the development of depression, especially […]

Just as no two people are alike, there are no two equally suffering depressed patients. The International Classification of Diseases 10th edition does not provide for the isolation of the leading syndrome, but identifies only two variants of depression: Depressive disorder with somatic symptoms; Depressive disorder with psychotic manifestations. The American classification of mental illness […]

There is a growing number of people with Alzheimer’s disease. At the age of 85, the disease occurs in 50% of patients. Depression accompanies Alzheimer’s disease and is diagnosed in 30-50% of patients. It is depression that exacerbates the symptoms of Alzheimer’s disease — passivity, leads to the need for early patient care, and increases the risk of mortality. Diagnosis […]

The concept of the functionality of some mental illnesses should be a thing of the past. An unidentified reason is not a reason to talk about the functionality of mental illness. Advances in technology have made it possible to find the cause of some mental illness. Changes in brain structures in patients with major depressive disorder and bipolar […]

Antidepressants usually increase the ability of the body’s cells to fight off infection (phagocytosis), such as viruses and bacteria. Note that antidepressants do not affect vitamins, the level of some trace elements in the patient’s blood. It has been shown that the function of cells of the immune system can be regulated by the nervous system […]

Chinese scientists have found that depression and anxiety are associated with structural changes in the human brain. Scientists will talk about their work at the annual convention of the Radiological Society of North America, which will be held from November 26 to December 1 in Chicago. Scientists were interested in two conditions: clinical depression (or major depressive disorder, MDD) […]

Scientists at Imperial College London have found that psilocybin , a substance found in hallucinogenic mushrooms, alters the activity of neural circuits associated with mood. Research published in Scientific Reports . The study involved 19 people with chronic depression that did not respond to treatment. During the first week, the volunteers took 10 mg of psilocybin . Over the next seven days, participants took 25 mg of psilocybin . The […]

The Russian physician found out that disturbances in the perception of emotions arise as a defensive reaction. A trait known as alexithymia helps a person avoid depressive disorders under stress. The study was published in the Journal of Psychosomatic Research . Alexithymia is a psychopathic trait, the characteristic features of which are that a person does not know how to recognize his own and other people’s emotions, […]

Russian researchers have shown that in Russia a person who puts public interests above their own is at risk of suffering from depression. The study, supported by a grant from the Russian Science Foundation (RSF), was published in the journal Personality and Individual Differences . It is known that individualism dominates in the developed Western countries, especially in the United States, and collectivism in East […]

Scientists from Stanford University and colleagues found a group of neurons in the brains of mice, the removal of which made the animals breathe more slowly and feel calmer. The research is published in the journal Science . Slow, controlled breathing has been used for centuries to calm the mind and maintain mental health. Breathing techniques are also used, for example, […]